Hypoxia response is a biological phenomenon where cells, tissues, or organisms adapt to low oxygen levels in their environment. The response to hypoxia involves a complex network of signaling pathways and gene expression changes that help the organism survive and thrive under low oxygen conditions. This area of research is important in various fields such as cancer biology, cardiovascular disease, and high-altitude physiology, as understanding how cells respond to hypoxia can provide insights into disease mechanisms and potential therapeutic targets.